Seizures after aminophylline by suppository.
نویسندگان
چکیده
منابع مشابه
Pharmacological studies on mechanisms of aminophylline-induced seizures in rats.
In the present study, the possible role of free radicals in aminophylline-induced seizures was evaluated in albino rats. Aminophylline (theophylline in ethylene diamine; 50 - 300 mg/kg) induced convulsions in rats in a dose-dependent manner, and both incidence of seizure and mortality were maximum at 300 mg/kg. Conventional anti-epileptics, diphenylhydantoin and dizocilpine, as well as adenosin...
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This work investigated the association of acute ethanol and aminophylline administration on behavioral models of depression and prefrontal monoamine levels (i.e. norepinephrine and dopamine) in mice. The animals received a single dose of ethanol (2 g/kg) or aminophylline (5 or 10 mg/kg) alone or in association. Thirty minutes after the last drug administration, the animals were assessed in beha...
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Aminophylline is determined by cathodic stripping voltammetry (CSV) in BR buffer, pH 7.5 at a hanging mercury drop electrode. The detection limit was 3x10 M after 60 s accumulation at -0.60 V versus Ag/AgCl reference electrode. The linear range demonstrated up to 5x10 M using CSV. The interference caused by some purine derivatives, anions and some metal cations on the peak current was studied. ...
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The aim of this study was to evaluate the effects of H(1) (antazoline and astemizole) or H(2) (cimetidine and famotidine) histamine receptor antagonists on the clonic phase, tonic seizures and morality of mice challenged with aminophylline to induce convulsions in mice. Moreover, the total plasma and brain concentrations of theophylline were evaluated. Astemizole (1 mg/kg) did not affect the th...
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ژورنال
عنوان ژورنال: BMJ
سال: 1979
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6188.497-c